منابع مشابه
Acral Hemorrhagic Darier Disease.
Darier disease is an autosomal-dominant inherited condition caused by mutation of a gene, which produces a protein involved in calcium channel regulation. The disease has a variety of manifestations and lacks consistent genotype-phenotype correlations. Acral hemorrhagic Darier disease causes macules, papules, vesicles and/or hemorrhagic blisters on the extremities. Other classic signs of the di...
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Transmission is by the fecal-oral route. Pili (fimbriae) allow the bacteria to colonize the ileal mucosa. Cytotonic enterotoxins (encoded on plasmid or bacteriophage DNA) induce watery diarrhea. Plasmid-encoded invasion factors permit invasion of the mucosa, and plasmidor bacteriophage-encoded cytotoxic enterotoxins induce tissue damage; the presence of either of these factors induces a host in...
متن کاملEpidemic Diarrheal Disease of Suckling Mice
1. The disease was almost certainly infectious. 2. Its eradication offered much greater practical difficulties than are presented by certain other infections of mice. 3. A definite tendency toward greater susceptibility in first litters as contrasted with subsequent ones was noted. 4. Advantage could be taken of this increasing resistance to keep the infected colony in efficient production, but...
متن کاملDoes Poor Water Quality Cause Diarrheal Disease?
Since the time of John Snow we have known that contaminated water can lead to outbreaks of waterborne disease. This association is commonly acknowledged by both the scientific community and the lay public. But among those who study water quality and diarrheal diseases, the association is muddied by many nuanced questions. For example, what is the relative contribution to the burden of diarrheal...
متن کاملAn Epidemic Diarrheal Disease of Suckling Mice
Intranuclear inclusions were found in 75 per cent of young mice suffering from a spontaneous diarrheal disease. They were confined to the epithelial cells of the small intestine, and to the intestinal and mesenteric lymphadenoid tissue. They were seen only between the 10th and 15th days after birth, in apparently healthy control mice of the same age group, they were found in only two of thirty-...
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ژورنال
عنوان ژورنال: Muller Journal of Medical Sciences and Research
سال: 2018
ISSN: 0975-9727
DOI: 10.4103/mjmsr.mjmsr_45_17